Evaluation to population genetics data

Project description

You have been given a dataset containing Identifiler® genotypes from 200 individuals. Your first task is to analyse this dataset in terms of its potential usefulness as a database for individual identification purposes. <br />

In an investigation being carried out in an Arab country, a match has been observed between a DNA profile generated from a crime scene stain and the DNA profile generated from a white Caucasian male arrested by police. The DNA profile generated is shown below:

D8S1179 8, 17<br />
D21S11 34, 34.2 <br />
D7S820 9, 9<br />
CSF1PO 8, 14<br />
D3S1358 14, 14<br />
TH01 8, 10<br />
D13S317 9, 10<br />
D16S539 14, 15<br />
D2S1338 19, 19<br />
D19S433 11, 14.2<br />
vWA 18, 18<br />
TPOX 10, 10<br />
D18S51 11, 19<br />
D5S818 8, 9<br />
FGA 18.2, 19.2<br />
<br />
<br />
Match probability estimates using this database have been provided for the investigation but the defence team has raised the inappropriateness of the database as an issue. <br />
<br />
<br />
Your second task is to evaluate why the defence team may have raised this issue.<br />
You must present your results in a scientific manner (take a look at published articles) detailing every analysis carried out and discussing the results obtained. <br />
<br />
Learning outcomes<br />
This assessment will test your ability to meet the following learning outcomes described in your module booklet:<br />
<br />
1. Apply the principles of population genetics to forensic science.<br />
2. Analyse and assess genetic data using different population genetic software.<br />
3. Critically evaluate genetic data using statistical analyses for forensic purposes.<br />
4. Present and defend the rationale of forensic DNA evidence in relation to population genetics theory. <br />
5. Discuss and evaluate critically the genetic relationships of individuals and populations.<br />
<br />
<br />
Assessment Criteria<br />
<br />
1. Evidence of thorough data analysis skills.<br />
2. Evidence of ability to interpret results accurately.<br />
3. Evidence of wide reading and comprehension.<br />
4. Evidence of incorporation of independent thought.<br />
<br />
<br />
—<br />
Referencing Requirements:<br />
References<br />
ABDIN, L., et al. 2003. Analysis of 15 short tandem repeats reveals significant differences between the Arabian populations from Morocco and Syria. Legal Medicine, 5, Supplement, S150-S155.<br />
AKBASAK, B. S.,et al. 2001. Turkish population data with the CODIS multiplex short tandem repeat loci. Forensic Science International, 123, 227-229.<br />
ALENIZI, M., GOODWIN, W., ISMAEL, S. & HADI, S. 2008. STR data for the AmpFlSTR® Identifiler® loci in Kuwaiti population. Legal Medicine, 10, 321-325.<br />
ALSHAMALI, F., ALKHAYAT, A. Q., BUDOWLE, B. & WATSON, N. D. 2005. STR population diversity in nine ethnic populations living in Dubai. Forensic Science International, 152, 267-279.<br />
BALDING, D. J. & NICHOLS, R. A. 1994. DNA profile match probability calculation: how to allow for population stratification, relatedness, database selection and single bands. Forensic Science International, 64, 125-140.<br />
BARNI, F. et al. 2007. Allele frequencies of 15 autosomal STR loci in the Iraq population with comparisons to other populations from the middle-eastern region. Forensic Science International, 167, 87-92.<br />
BRANDT-CASADEVALL, C., et al. 2003. Tunisian population allele frequencies for 15 PCR-based loci. International Congress Series, 1239, 113-116.<br />
BUCKLETON, J., TRIGGS, C. M. & WALSH, S. J. 2005. Forensic DNA Evidence Interpretation, CRC Press.<br />
BUCKLETON, J. S., CURRAN, J. M. & WALSH, S. J. 2006. How reliable is the sub-population model in DNA testimony? Forensic Science International, 157, 144-148.<br />
BUDOWLE, B. et al. 1999. Population data on the thirteen CODIS core short tandem repeat loci in African Americans, U.S. Caucasians, Hispanics, Bahamians, Jamaicans, and Trinidadians. J Forensic Sci, 44, 1277-1286.<br />
CARRACEDO, et al. 2013. New guidelines for the publication of genetic population data. Forensic Science International: Genetics, 7, 217-220.<br />
CHEN, J.-G., PU, H.-W., CHEN, Y., CHEN, H.-J., MA, R., XIE, S.-T. & ZHANG, L.-P. 2012. Population genetic data of 15 autosomal STR loci in Uygur ethnic group of China. Forensic Science International: Genetics, 6, e178-e179.<br />
CZARNY, J. et al 2005. Genetic variation of 15 STR loci (D3S1358, vWA, FGA, TH01, TPOX, CSF1PO, D5S818, D13S317, D7S820, D16S539, D2S1338, D8S1179, D21S11, D18S51, and D19S433) in populations of north and central Poland. Forensic Science International, 147, 97-100.<br />
ELMRGHNI, S. et al 2012. Genetic data provided by 15 autosomal STR loci in the Libyan population living in Benghazi. Forensic Science International: Genetics, 6, e93-e94.<br />
EXCOFFIER, L., LAVAL, G. & SCHNEIDER, S. 2007. Arlequin (version 3.0): An integrated software package for population genetics data analysis. Evolutionary Bioinformatics, 12, 0-0.<br />
EXCOFFIER, L. & LISCHER, H. E. L. 2010. Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Molecular Ecology Resources, 10, 564-567.<br />
GOODWIN, W., LINACRE, A. & HADI, S. 2011. An Introduction to Forensic Genetics, Wiley-Blackwell.<br />
HARTL, D. L. & CLARK, A. G. 2007. Principles of Population Genetics, Sinauer Associates.<br />
HILL, C. R., DUEWER, D. L., KLINE, M. C., COBLE, M. D. & BUTLER, J. M. U.S. population data for 29 autosomal STR loci. Forensic Science International: Genetics.<br />
KOROSTISHEVSKY, M. et al. 2004. Erroneous identification in a mixed population: simulation using Israeli STR data. International Journal of Legal Medicine, 118, 111-114.<br />
LEWONTIN, R. C. 1995. The Apportionment of Human Diversity. In: DOBZHANSKY, T., HECHT, M. & STEERE, W. (eds.) Evolutionary Biology. Springer US.<br />
OMRAN, G. A., RUTTY, G. N. & JOBLING, M. A. 2009. Genetic variation of 15 autosomal STR loci in Upper (Southern) Egyptians. Forensic Science International: Genetics, 3, e39-e44.<br />
PORRAS, L., BELTRÁN, L., ORTIZ, T., SANCHEZ-DIZ, P., CARRACEDO, A. & HENAO, J. 2008. Genetic polymorphism of 15 STR loci in central western Colombia. Forensic Science International: Genetics, 2, e7-e8.<br />
RUBI-CASTELLANOS, R., ANAYA-PALAFOX, M., MENA-ROJAS, E., BAUTISTA-ESPAÑA, D., MUÑOZ-VALLE, J. F. & RANGEL-VILLALOBOS, H. 2009. Genetic data of 15 autosomal STRs (Identifiler kit) of three Mexican Mestizo population samples from the States of Jalisco (West), Puebla (Center), and Yucatan (Southeast). Forensic Science International: Genetics, 3, e71-e76.<br />
TEREBA, A. 1995. Tools for analysis of population statistics. Profiles DNA, 2, 14-16.<br />
<b

term papers to buy
research papers

Order a unique copy of this paper
(550 words)

Approximate price: $22

Basic features
  • Free title page and bibliography
  • Unlimited revisions
  • Plagiarism-free guarantee
  • Money-back guarantee
  • 24/7 support
On-demand options
  • Writer’s samples
  • Part-by-part delivery
  • Overnight delivery
  • Copies of used sources
  • Expert Proofreading
Paper format
  • 275 words per page
  • 12 pt Arial/Times New Roman
  • Double line spacing
  • Any citation style (APA, MLA, Chicago/Turabian, Harvard)

Our Guarantees

101papers.com is always working towards customer satisfaction. Our professional academic writers always aim at producing comprehensive papers that possess quality and originality at pocket-friendly prices. Students are assured that all their private information is safe with us.

Money-Back Guarantee

101papers.com provides a system where students can request for money-back in case they cancel the order or in the rare instances of dissatisfaction. The refund policy adheres to the company’s term and conditions on money-back.

Read more

Zero-Plagiarism Guarantee

While providing the best professional essay writing services, we guarantee all our students of plagiarism-free papers. All papers produced by our professional academic writers are checked against all web resources and previously completed papers to avoid plagiarism.

Read more

Free Revision Policy

In our urge to provide the best professional essay writing services, we guarantee students of free revision policy. The free revision policy is a courtesy service where students can request for unlimited for their completed papers. We always aim at achieving 100% customer satisfaction rates. The free revision policy is one among many of our major advantages.

Read more

Privacy Policy

At 101papers.com, every student is entitled to total security. Our professional academic writers are always committed to protecting all private information of our customers. We do not share any personal information with third parties. Additionally, we provide safe systems for all online transactions.

Read more

Fair-Cooperation Guarantee

Working with us is the greatest step towards achieving all your academic goals. We always deliver the best professional essay writing services as promised. We, therefore, expect all students to work cooperatively with us, as we work towards achieving our goal, your satisfaction. This way, all services will be delivered accurately and on time.

Read more

Calculate the price of your order

550 words
We'll send you the first draft for approval by September 11, 2018 at 10:52 AM
Total price:
$26
The price is based on these factors:
Academic level
Number of pages
Urgency