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Experiment 1: Following Chromosomal DNA Movement through Meiosis

Part 1 – Meiotic Division Bead Pictures without Crossing Over – You must provide pictures of your bead manipulations at each stage.

Prophase I

Metaphase I

Anaphase I

Telophase I

Prophase II

Metaphase II

Anaphase II

Telophase II

Cytokinesis

Part 2: Meiotic Division Beads Diagram with Crossing Over – You must provide pictures of your bead manipulations at each stage.

Prophase I

Metaphase I

Anaphase I

Telophase I

Prophase II

Metaphase II

Anaphase II

Telophase II

Cytokinesis

Post-Lab Questions

1.    Were any of your daughter cells genetically identical at the end of Part I above?  What about Part II?  What does this tell you about the importance of crossing over?

2.    What must occur during interphase for meiosis to be successful?

3.    When does the diploid number become haploid during meiosis?

4.    Why did you use non-sister chromatids to demonstrate crossing over?

5.    What combinations of alleles could result from a crossover between a chromosome having genes BD and a chromosome having genes bd?

6.    Blue whales have 44 chromosomes in every cell. Determine how many chromosomes you would expect to find in the following:

Sperm Cell:

Egg Cell:           

Daughter Cell from Meiosis I:

Daughter Cell from Meiosis II:

7.    What is the difference between a chromosomal mutation and a gene mutation?

8.    Diagram what would happen if sexual reproduction took place for four generations using diploid (2n) cells.

1.    What is your hypothesis as to what differences you might observe when comparing the karyotypes of human cells which experience normal cell cycle control versus cancerous cells (which experience abnormal, or a lack of, cell cycle control)?

2.    Did your results confirm or disprove your hypothesis?  Why or why not?  Be specific!

3.    Suppose a person developed a mutation in a skin cell which results in cancer, but the cancer was effectively treated with a cocktail of cancer-fighting techniques. Is it possible for this person’s offspring to inherit this cancer-causing mutation? Why or why not?  Be specific!